Popular Drugs Catalogue



Chemical Name: NEFAZODONE (ne-FAZ-o-done)

Common uses
This medicine is an antidepressant used to treat depression.

Before using
WARNING: Nefazodone rarely may cause serious (potentially fatal) liver disease. Seek immediate medical attention if you develop: dark urine, extreme fatigue, persistent loss of appetite, stomach pain, yellowing eyes/skin. Tell your doctor or pharmacist if you have a history of liver problems or abnormal liver function tests (LFTs) before taking this medicine. Your doctor may perform laboratory tests (e.g., liver function) to monitor your progress. If your doctor stops your nefazodone treatment because of liver problems/abnormal liver tests, you should not take this drug again. Consult your doctor or pharmacist for more details. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are also taking cisapride, astemizole, a monoamine oxidase inhibitor (MAOI), terfenadine, tramadol, or carbamazepine. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking a benzodiazepine (e.g., diazepam, alprazolam), buspirone, warfarin, or fluoxetine. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you have liver disease. Inform your doctor of any other medical conditions, allergies, pregnancy, or breast-feeding. Contact your doctor or pharmacist if you have any questions or concerns about using this medicine.

Follow the directions for using this medicine provided by your doctor. STORE THIS MEDICINE at room temperature between 59 and 86 degrees F (15 and 30 degrees C) in a tightly-closed container, away from heat and light. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT take 2 doses at once.

IF YOU HAVE HAD A SEVERE ALLERGIC REACTION to trazodone, contact your doctor or pharmacist BEFORE TAKING THIS MEDICINE. A severe allergic reaction includes a severe rash, hives, breathing difficulties, or dizziness. IT MAY TAKE SEVERAL WEEKS for this medicine to work fully. Do not stop taking this medicine without checking with your doctor. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are taking this medicine. Medical and/or laboratory tests such as liver function tests may be performed to monitor your progress or to check for side effects. ADDITIONAL MONITORING OF YOUR CONDITION is recommended at the start of treatment with this medicine and whenever a change to your dose is made. If you experience anxiety, agitation, panic attacks, difficulty sleeping, irritability, hostility, impulsive feelings, severe restlessness, or worsening of depression contact your doctor as soon as possible. These may be signs that your condition is worsening or that your treatment with this medicine should be evaluated. If you are a parent or caregiver of a patient that is taking this medicine, it is important for you to watch for these symptoms. Contact the doctor as soon as possible if any of these symptoms occur. Contact your doctor for more information. DO NOT DRIVE, OPERATE MACHINERY, OR DO ANYTHING ELSE THAT COULD BE DANGEROUS until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. THIS MEDICINE WILL ADD TO THE EFFECTS of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. DO NOT TAKE SELDANE (terfenadine), HISMANAL (astemizole), or cisapride while taking this medicine. CAUTION IS ADVISED WHEN USING THIS MEDICINE IN CHILDREN because they may be more sensitive to the effects of this medicine. FOR WOMEN: IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. IT IS UNKNOWN IF THIS MEDICINE IS EXCRETED in breast milk. IF YOU ARE OR WILL BE BREAST-FEEDING while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects
SIDE EFFECTS, that may go away during treatment, include headache, dry mouth, drowsiness, dizziness, weakness, constipation, lightheadedness, or mental confusion. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience blurred vision, irregular heartbeat, or seizures. CONTACT YOUR DOCTOR IMMEDIATELY if you experience thoughts of hurting yourself, mental or mood changes, or worsening of depression. Nefazodone can rarely cause serious, possibly fatal, liver problems. CONTACT YOUR DOCTOR IMMEDIATELY if you experience nausea, vomiting, stomach/abdominal pain, yellowing eyes or skin, dark urine, or unusual tiredness or weakness. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

If you take too much
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include nausea, vomiting, sluggishness, and increased sweating.

Additional information
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.